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In general, every aspect of human physiology is based on the balance between polar opposite between the Yin and the Yang, this creates homeostasis. When we look at specific parts of our physiology like the immune system, the yin and the yang, the opposite will be anti-inflammation and the inflammation; the negative and the positive. When those two things are in balance, your immune system is functioning properly. If we’re talking about our nervous system, then we’re talking about the forces of excitation and the forces of inhibition or relaxation. We’re talking about our endocrine system or our hormone system, we have the forces of breaking down tissue or the catabolic hormones and we have the anabolic hormones which build up tissue. When those two forces are in balance, we have homeostasis of our endocrine or our hormone system. If we’re talking about oxidation, we have forces of anti-oxidation and forces of oxidation. Most people think that you have to just take buckets of anti-oxidants all the time as if oxidation is bad. Not true, if you did not have oxidation and the forces of oxidation in your body, you couldn’t survive one minute. Those two things have to be in balance, they have to be in homeostasis, all of our physiological systems have to be in this constant state of homeostasis, a dynamic balance. The stronger your physiological ability to stay in homeostasis is, the more robust your capacity to be in homeostasis, the healthier you are.
Next question; what exactly is dynamic balance? This is kind of difficult to understand and the best way is a model; a model of a mobile. So here we go, you’re looking at a mobile, you’ve probably played with this when you were a kid perhaps you even have some of this in your home right now. We have all of these horizontal elements with little strings hanging down from them and we have the stars hanging at the bottom. In this particular model, the stars represent signaling molecules. If this is a model of your neurology, the stars that are hanging will be the neuro transmitters. If this was a mobile of your endocrine system, your hormone systems, then the hanging stars will be hormones. And if this was your immune system, the hanging stars will be cytokines; these are the signaling molecules that make your immune system work. Now, what makes this a dynamic balance is as you know, if you change anything in this mobile, it affects everything in this mobile. Let’s say for example that the star here at the bottom that’s now big and swollen and red, its weighted down as if you took a paper clip of some weight and attached it to the mobile hanging in your home. That star is going to pull down and everything in the mobile is going to shift. You can’t change any one element, without affecting every element in the mobile. What’s interesting however, is that initially the mobiles going to go through these oscillations where things are bouncing up and down and shifting up and down until the oscillation slowly quiets and the mobile finds a new state of homeostasis, a new point of balance. Now, everything is shifted in the mobile, the stars are all in different locations now and many of the sticks are no longer horizontal, they’re kind of twisted to one angle or the other but our physiologies are so smart that they’ll find a new point of balance. During the shifting in the oscillation, is when you feel sick, when you have symptoms but our body, our physiology will compensate and a new balance will be found and you can continue to function. Now let me explain how modern medicine with pharmaceutical drugs interact with the system. Let’s say you have another one of these stars, another one of these elements that goes a little bit ahwire; this star over here on the left. So you’re feeling lousy and you go to the doctor and the doctor does some kind of test and decides okay we need to give you a drug and so you take a drug, some kind of pharmaceutical drug to deal with this one element over here on the left that’s now going somewhat haywire. And the drug is designed to clamp down on those symptoms. Notice that the drug is designed to deal with exactly that one star, not the entire system of the mobile but that one start and the symptoms that its creating. However, we know that pharmaceutical drugs have many, many unintended side effects and so because of the drug you’re taking now another star goes haywire and you have more symptoms and now you have to take a drug to counter act the symptom from the first drug and then you clamp down on that star as well. And when the third one goes haywire, and so you clamp down on that one as well. And let’s say now, you seem to be stable, you seem to be functioning and everything is copasetic. Is it really? Everything seem to be stable here because the mobile isn’t shifting anymore but let’s take a closer look at your system. This is actually what’s happening, you now have all sorts of artificial weights attached to your physiology, to your mobile. You can see that your physiology is under a lot of stress. The weight of all this different drugs and this over expressed stars are pulling down heavily on this mobile and you can see that some of those bars are now bent because of so much tension. One more little thing going wrong with your physiology, perhaps it’s something as simple as a cold or a virus or some kind of drug interaction that you didn’t anticipate and now something breaks; this system is under so much tension and so much stress that the oscillations will be huge and you might find yourself in the ICU under life support. So in a nut shell, pharmaceutical drugs work at the level of the symptoms, not the systems which causes enormous strains on you human physiology. So I’ve showed you this in order to point out, to highlight the differences between how pharmaceutical drugs work at the level of the stars and how CBD works.
CBD, instead of working at the level of the stars, works at the level of the system of balance, at the nexus of balance that will be in these crystalline green hubs where the string attaches to the stick. That’s where the system knows if it’s in balance or out of balance. It can’t tell what’s happening at the level of the star but it knows what is happening right there in that green crystalline hub where balance is maintained and established. So in the model that we are using, the mobile to highlight how our physiology works; that’s where CBD works. Now in our actual physiology where the CBD work, lets take a closer look. Here we go, we’re going to travel into out physiology, right into our central nervous system. Now we’e going to see at the level of our individual cells. That the cell surface is covered with this green receptors. These are receptors for CBD and when the CBD binds to that receptor, it sends a message into the cell which travels all the way down into the nucleus of the cell where the intelligence of our entire physiology is contained within our chromosomes. So here a chromosome is going to unwind and you’re going to see the actual DNA that contains the codes for everything our body does; this is like the software that runs our physiology.
Genes are the codes for every protein that our body makes including all the signaling molecules that runs our physiology such as our Neurotransmitters that run our nervous system, our hormones that runs our endocrine system and Cytokines that run our immune system. So imagine for instance that these are cells in your pancreas making insulin. These is happening in a million cells let’s say, all producing huge amount of insulin to keep your blood sugar in proper balance. Again your insulin is a hormone which is a protein. So we see that throughout our physiology, we have receptors specifically designed to bind with CBD and CBD has its effect on the nucleus of our cells where proteins are being made. So which proteins are being made from the influence of CBD? CBD modulates the transcription of over 1100 Genes that make the signaling molecules that naturally reduce inflammation in our central nervous system and throughout our immune system. Restoring homeostasis to both our immune and central nervous system. So as you can see on the left side of the slide, CBD up regulates the genes that create anti-inflammatory biochemical for our immune system and up regulates the Gaba system in our central nervous system which brings calmness to our central nervous system. And on the right side of the slide, we can see that CBD down regulates the genes that create inflammatory bio-chemicals in our immune system and also down regulates the glutamine system in our central nervous system which causes over excitation.
So now, let’s go back to the model of our physiology and see how CBD affects it. We go back to our one star that’s out of lack and now we introduce CBD and we see a cascade going through all the points of balance and the mobile comes back to homeostasis, its original stable beautiful balance. Now our physiological system is far more complex than the simple mobile that I’ve been showing you here with only 12 stars. For instance, our immune system has approximately 350 different signaling molecules on it. So it’s an enormous mobile, which also explains why there’s so many unintended drug interactions, because if you affect one of those little stars, it’s going to shift all 350 of those other stars and who could possibly figure that out. In fact, this is what our immune system actually looks like and of course, when you introduce CBD, to our amazingly complex physiology, in the immune system, the cascade of homeostasis trickles down through all 350 of those stars. It’s a beautiful thing. Bottom-line, CBD causes a cascade of homeostasis through our entire central nervous system and our entire immune system, so why is this happening? Because as I mentioned before, we have receptors in our physiology for CBD this is called the “Endo-Cannabinoid System”. Back in medical school, we didn’t even know about the end-cannabinoid system, it was only discovered in the 1990’s by Dr. Rafael Mechoulam from the Hebrew University in Israel where an amazing amount of incredible biomedical technology innovations are coming from that tiny little country. So the endo-cannabinoid system is a network of cells throughout our body that have receptors for CBD. In fact there are more receptors for CBD in our body than any other kind of receptors. So the endo-cannabinoid system is truly the largest network of its kind throughout our entire physiology. Among other things, Dr. Mechoulam also discovered that we make our own cannabinoids in our body, this is Anandamide and 2AG. Anandamide, is something that we create when we are meditating, hence it’s called the bliss molecule and 2AG as well as Anandamide are released in mothers milk when a child is breast feeding. So no wonder that child is so calm and happy when they’re breast feeding. Those two compounds are also associated with a runners high, you know that point when you’re running and suddenly you’re in bliss, you kind of breakthrough he wall and now you just feel wonderful. Those two are natural cannabinoids that our own body make and bind to our CBD receptors. So here we have our CBD receptors in our central nervous system and then our cardiovascular system where our immune cells are constantly circulating. Of course in our bone marrow where the cells are actually manufactured and of course, in our immune organs. Our major immune organs are the intestines, the spleens and the bladder
And last but not the least the lymph system. So our bodies are filled with CBD receptors. So what? Now you know the story. Why is this important? Why does this matter? Why is this important to you or me? Or if you’re interested in the business of distributing CBD, why is this important to humanity? If you live in Urban America or urban anywhere, in the world, you are inflamed. Your central nervous system is inflamed as well as your immune system is inflamed and nobody is exempt because our physiological systems are under assault. Assaults from environmental toxins such as; herbicides, insecticides and heavy metals. Chronic biological infections such as; bacteria, viruses, fungus and molds and last but not least our inflammatory diets which are very poor usually with too much sugar which causes leaky guts and inflamed gut that allows certain bacterial infestations to occur that gets into our blood and into our systems. So what kind of symptoms, what kind of stress do all these things cause to us? If your immune system is inflamed, you might be suffering from autoimmune diseases like rheumatoid arthritis, inflamed bowel disease, lupus and thyroid or fibromyalgia or even MS and you skin; psoriasis or eczema and all sorts of other chronic infections. Do you realize, many of these things didn’t even exist a 100 or 150 years ago? Incidence of this kind of disease is growing throughout the last century because of the environmental loads of toxins that we’re now absolving into our systems.
Now let’s take a look at the central nervous systems. If it is inflamed, what kind of things might you be suffering from; brain fog, migraine, epilepsy, anxiety and PTSD, ADD, ADHD, Autism and insomnia. Again, a 100 or 150years ago, these kinds of symptoms, these kinds of diseases were really rare and over the last 150 years because of the insult, the ongoing insults to our systems, these kind of things are more and more prevalent with every single year. So if you are suffering from any of these conditions, CBD might provide you with tremendous healing, tremendous relief, and right through your own natural endo-cannabinoid system that brings homeostasis both to your immune system and to your central nervous system.
So in conclusion, whatever you learn from these conversations, that health is achieved through physiological homeostasis right through our endo-cannabinoid system and therefore, CBD is an indispensable catalyst for optimal health. For those of you that might be interested in the business of the distribution of CBD and the marketing, the creating of the market for CBD? This card is a summary of all the important points we covered in this lecture. On one side of the card is the side by side comparison of a pharmaceutical version of CBD versus the single most effective formulation of CBD available on the market today. It is a proprietary nano liposome technology that allows for the oil to be placed under your tongue subliminally where it will get absorbed directly into your blood stream. We like to call that IV power with the convenience of sublimal administration; it’s really cool, a pump under the tongue and it goes straight into your blood stream. This formulation, liposomal Nano formulation is 6 times more absorbable or bio available than even the pharmaceutical grade. It is very important that you understand that, because not only is this this most physiological effective, it is also the most cost effective formulation on the market. This proprietary uposomal technology was developed by Dr. Christopher Shade of Quicksilver Scientific. He’s famous in the world of functional and integrative medicine and his proprietary formulations are used by a thousand of doctors around the world with their patients every day. On the other side of the card, is a summary of all those kind of conditions and symptoms that a person might be suffering from if they have central nervous system inflammation or immune inflammation, therefore easy reference. You’ll also notice point 3 and 4 CBD reduces pain. So if you know someone suffering from a lot of pain, probably from chronic inflammation, the CBD will really help. Also number 4, CBD promotes our body’s ability to naturally detoxify. So at the bottom of the card, you’ll see a reference to CBD science email@example.com. If you go to that particular website, you will find thousands of references right through the government’s own NIH website which is the repository of all of the articles, all of the clinical scientific studies that are being conducted today on CBD and all the different conditions that it affects positively. So for all of you who have joined me on this remarkable odyssey into our physiology in order to understand the effects of CBD on our health and our wellbeing; good luck to you. CBD can make a huge difference in your health and wellbeing and for all of you who are interested in the distribution of CBD, the business of CBD both here in the US and worldwide, good luck to you and god speed. It’s an important business, a very significant business that will make a huge difference both in the lives of people you know and care about and the life of humanity throughout the planet, good luck.